Andrea Ravasio

Position
Assistant Professor
Academic unit
  • Institute of Biological and Medical Engineering
Lines of Research
  • Cell and Tissue Mechanobiology
  • Cancer research
  • Microfabrication and enabling technologies for biotechnology
  • Microscopy and image analysis
  • Computational modeling and artificial intelligence.
Summary

Prof. Ravasio obtained his M.Sc. degree in Biology at the University of Milan (Italy) in 2004 with an experimental study on cell volume regulation by investigating in-vivo nanoscale protein-protein and protein-plasma membrane interactions. He obtained his PhD in Physiology at the University of Innsbruck (Austria) in 2009. Among his findings during his PhD studies are the role of mechanical forces in the regulation of lung alveolar physiology.

Some time later, Dr. Ravasio moved to Singapore where he investigated the biomechanics of collective cell migration; the molecular and tissue-scale dynamics regulating epithelial tissue organization; and the establishment of population heterogeneity in stem and cancer cells (Mechanobiology Institute and Singapore-MIT Alliance for Research and Technology, Singapore).

In the Laboratory of Mechanobiology of Transforming Systems, Professor Ravasio together with the laboratory's research group seek to understand the biomechanics of biological systems and their contribution to various pathological states. In this context, the research group is developing high impact studies to probe the interaction between forces and biological material from molecular to tissue level. To learn more about Professor Ravasio's research career visit his personal website here.

  • Biologist with major in Physiology, Italy, 2004. -PhD, Department of Physiology and Biomedical Physics, Medical University of Innsbruck, Austria, 2009.

Current Projects
Fondecyt Regular Nr. 1210872 (2021-2025). "Multiscale dynamics and active matter processes
regulate tensional homeostasis of cellular aggregates". Principal Investigator. Amount of
financing: 244,533,000 CLP.

Fondecyt Regular Nr. 1220804 (2022-2026). "Effect of advanced glycation end-products on
Streptococcus mutans dysbiotic colonization in root caries". Coinvestigator. Amount of
financing: 277,441,040 CLP.

Fondecyt Regular Nr. 1210872 (2021-2024). "Mechanical constraints induce traveling waves of gene
expression in cell colonies". Coinvestigator. Amount of financing: 244,000,000 CLP.

Previous Projects

Fondequip Nr. EQM210101 (2021 - 2023). "Microfluidic Device Fabrication System and
Biomimetic Cellular Environment for Frontier Biomedical Research". Principal
Investigator. Funding amount: 216,581,000 CLP.

VRI-UC BRIDGE 012/2020 (2020). "Mechanical homeostasis in epithelial and cancer cell aggregates".
Principal Investigator. Amount of financing: 4,000,000 CLP.

VRI-UC BRIDGE 004/2019 (2019). "Molecular Biomechancis of Epithalial cells and Implications in
Carcinoma Transformation". Principal Investigator. Funding amount: 7,000,000 CLP.
Ring Project ACT192015 (2019 - 2023). "Multiscale mechanics and self-organizing processes in
developing systems". Director of research program. Amount of funding: 450,000,000 CLP.

Luksic Family Collaboration Grant (2020). "Interrogating the Bioacoustic Effect for Potential
Application in the Management of Cystic Fibrosis". Pontificia Universidad Católica de Chile and
University of Notre Dame Collaboration Grant. Coinvestigator. Amount of financing: 10,000
USD.

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